Indomethacin: Uses, Side Effects, and What You Need to Know

When you need fast relief from swelling and pain, Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID) used to treat acute inflammation and pain. Also known as Indocin, it's one of the strongest NSAIDs available by prescription and is often chosen when other painkillers don't cut it. Unlike ibuprofen or naproxen, Indomethacin doesn’t just mask symptoms—it actively blocks the body’s inflammatory response at the source. That’s why doctors reach for it in cases like gout flare-ups, rheumatoid arthritis, or even certain types of headaches.

It’s not just about arthritis. People with bursitis, tendonitis, or even severe menstrual cramps have found relief with Indomethacin. But it’s not a gentle drug. Because it hits inflammation hard, it can also hit your stomach, kidneys, and heart hard too. That’s why it’s not something you take long-term unless absolutely necessary. Many patients use it for short bursts—like a week or two—during a bad flare-up, then switch to something milder. It’s also used off-label for patent ductus arteriosus in newborns, a rare but critical heart condition in premature babies. That’s how potent it is.

When you look at the posts here, you’ll see how Indomethacin fits into a bigger picture. It’s often compared to other NSAIDs, like diclofenac or celecoxib, but it’s not always the first choice because of its side effect profile. You’ll find real stories about how it helped someone with gout get back on their feet, or how another person had to stop it after stomach bleeding. Some posts dig into how it interacts with blood pressure meds or kidney function. Others compare it to corticosteroids or colchicine for gout treatment. There’s no sugarcoating here—just facts about what works, what doesn’t, and who should avoid it.

There’s a reason people search for Indomethacin price, alternatives, or side effects. It’s powerful, but it’s not for everyone. If you’re considering it, you need to know the risks as much as the rewards. The articles below give you exactly that: no fluff, no marketing, just what patients and doctors have learned through experience. Whether you’re managing chronic pain, dealing with a sudden gout attack, or just trying to understand why your doctor picked this drug over others, you’ll find real answers here.

A detailed look at how indomethacin works for osteoarthritis, covering dosing, evidence, safety, comparisons, and practical tips for doctors and patients.

Oct, 20 2025

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